This paper reports the instrumentation of a cylindrical balloon device for a wireless micro-sensor data acquisition system that can be used in diagnosing abnormalities in the esophagus. The proposed system is a battery-operated, microprocessor-based device that measures pressure from four absolute pressure sensors incorporated in a balloon positioned in the esophagus, stores the data in its memory, and transfers the data to a target board connected to the USB port of a PC computer at the end of a recording period. Stability and response time of the obtained voltage measurements related to pressure was tested in laboratory. Experimental measurements had stability and instantaneous response time for pressures in the range from 20 to 140 mm Hg. These results showed that the balloon device instrumented is suitable for monitoring intraluminal gastro-esophageal pressure to detect swallowing disorders. However, clinical trials are required to confirm the validity of the laboratory tests.